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Using Collagen Hybridizing Peptides to Improve IPF Diagnosis and Imaging

Anthony Kolton 0 Comments

     Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease marked by rapid progressive lung failure due to an accumulation of fibrotic collagen tissue. Due to the rapid onset of the disease, accurate and effective diagnostic tools are crucial for improving patient outcomes. Additionally, monitoring patient response to treatment should be minimally invasive...
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Collagen Hybridizing Peptides Conjugated to Water-Soluble Copolymers for Targeting Intratibial Osteosarcoma

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Discover innovative strategies for treating osteosarcoma (OS) with localized drug delivery using Collagen Hybridizing Peptides (CHPs). OS, a malignant bone cancer, often requires surgery and chemotherapy, but these treatments are plagued by systemic side effects. This research highlights the potential of CHPs to selectively target tumors by binding to damaged collagen in bone tissue.
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Detecting Early Arterial Damage in Atherosclerosis: How Collagen Hybridizing Peptides Overcome Diagnostic Challenges

Anthony Kolton 0 Comments

Atherosclerosis, characterized by the buildup of plaque inside human arteries, is one of the leading causes of cardiovascular diseases. The disease is brought on by a complex interplay between lipids, inflammatory cells, and the ECM. Arterial blood flow is restricted as plaques form, which can rupture to cause blockage. Arterial blockage, or occlusion, is...
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