Collagen Hybridizing Peptides Suggest a Correlation Between Collagen Degradation in and Recruited Inflammatory Cells in MI
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Collagen Hybridizing Peptides Suggest a Correlation Between Collagen Degradation in and Recruited Inflammatory Cells in MI
Myocardial Infarction (MI) is a leading cause of death globally. MI occurs when blood flow to parts of the heart are blocked long enough to cause tissue damage and/or death. Accurate diagnosis and assessment of myocardial fibrosis post-heart attack is crucial for effectively managing the disease. Left unchecked, fibrotic remodeling of arterial ECM can lead to stiffened heart muscle, reducing cardiac output and increasing susceptibility to additional cardiac events. Where traditional methods fail to detect fibrotic changes, Collagen Hybridizing Peptides offer a clearer picture.
Collagen Hybridizing Peptides allow researchers to actively monitor fibrotic changes to the myocardium and surrounding vasculature, facilitating a better determination of the tissue's fate. Abnormal ECM remodeling ultimately contributes towards the progression from Myocardial Infarction to chronic heart failure, remodeling which is not detectable without visualizing remodeling collagen with Collagen Hybridizing Peptides
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