NEWS: 3Helix and Roche publish groundbreaking research using CHPs to monitor subretinal fibrosis in vivo! | Learn More

NEWS: 3Helix named Startup of the Year at the University of Utah's Annual Innovation Awards! | Learn More

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BLOG: Liver fibrosis Detected with CHPs in half the time it takes with Picrosirius Red | Read Here

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Multiple Myeloma

Researchers Discover how CHPs Vividly Display Collagen Turnover During Cancer Development.

Studying the destruction of bone collagen and increased fibrosis in Multiple Myeloma is crucial for researchers as it provides insights into disease mechanisms, helps identify new therapeutic targets, and aids in developing treatments to mitigate bone damage and organ fibrosis. Collagen Hybridizing Peptides can aid researchers in quantifying osteolytic lesions resulting from Multiple Myeloma and monitoring fibrotic activity throughout the body. By using CHPs, researchers can gain precise, real-time data on collagen changes, improving their understanding of MM pathology and enhancing their ability to monitor treatment efficacy, ultimately leading to better patient outcomes.

Collagen Hybridizing Peptides open the door for similar research in other cancer types:

Myelodysplastic Syndromes (MDS)
Monoclonal Gammopathy of Undetermined Significance (MGUS)
Myeloproliferative Disorder (MPD)
And more

If you don't see the specific condition you're studying, it may be because we have yet to validate it; however, we are confident that Collagen Hybridizing Peptides will be effective in other osteologic conditions.

Citations

Bennink, Lucas L., et al. "Visualizing collagen proteolysis by peptide hybridization: From 3D cell culture to in vivo imaging." Biomaterials 183 (2018): 67-76.

金井沙也伽, and 小出隆規. "Possibility of new DDS using peptides that hybridize with denatured collagen" Drug Delivery System 35.3 (2020): 181-190.

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In respect of Products the Customer purchases from 3HELIX or our authorized distributors, 3HELIX grants the Customer only a limited, non-exclusive, non-transferable, non-sublicensable and royalty-free right under our intellectual property: you may only use the products you have bought, and only for your Internal Research Purposes. No right to transfer, distribute or resell our products or any of their components is conveyed expressly, by implication, or by estoppel. Unless expressly permitted by 3HELIX in writing, you will not modify, change, remove, cover or otherwise obscure any of our or our affiliates’ brands, trade or service marks on the products. Nothing in the Agreement limits our ability to enforce our intellectual property rights. 10.2 Commercial Applications; Additional Rights. Unless we expressly state otherwise in writing, 3HELIX gives no rights to use Products in any non-research commercial application, including manufacturing, quality control, or non-research commercial services such as reporting the results of your non-research activities for a fee or other consideration. If the Customer wishes to use a 3HELIX Product for any non-research commercial purposes, the Customer will require an additional license from 3HELIX by contacting info@3helix.com. 10.3 Intellectual Property Ownership. We exclusively own all intellectual property rights in any inventions (patentable or otherwise), discoveries, improvements, data, know-how, or other results that are conceived, developed, discovered, reduced to practice, or generated by you alone, by or for us, or jointly by you and us, in relation to processes, methods, or related synthesis of a custom product, or otherwise in connection with designing or manufacturing a custom product. 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Any notice or communication required or permitted under these Terms must be in writing and will be deemed received when personally delivered, or 3 business days after being sent by certified mail, postage prepaid, to a party’s specified address. 12.8 Requirement to Reduce to Writing. No waiver, consent, modification, amendment or changes to the terms of this Agreement will be binding unless in writing and signed by both of us. Our failure to object to terms contained in any subsequent communication from you will not be a waiver or modification of our Agreement. Updated Jan 16, 2018

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