Collagen Hybridizing Peptides (CHPs): Unraveling the role of Denatured Collagen in Neuroblastoma.
The complex interplay between the tumor microenvironment (TME) and cancer progression is a critical area of research, particularly in aggressive childhood cancers like neuroblastoma (NB). A recent study, “Unraveling the Role of Denatured Collagen in Neuroblastoma via Collagen Hybridizing Peptides,” published in July 2023, has shed light on the impact of thermal ablation on...
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Beyond Fibroblasts: CHPs provide Key Evidence for Keratinocyte-Driven Skin Development
Collagen is skin's foundation, but how it's truly built has been hidden – until now. Discover how see-through axolotls are providing an unprecedented window into this process, revealing secrets that could reshape skin science.
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Aging Unveiled: CHPs Reveal Widespread Tissue Damage and Reversible Collagen Breakdown in Aged Mice
Staining of collagen in multiple organs with Biotin-conjugated Collagen Hybridizing Peptides (B-CHPs). The black and white panels are an extraction of the fluorescent peptide signal, used for quantification of collagen damage. The universal process of aging involves the dysregulation of a wide spectrum of biological mechanisms. Using mouse models, DeLano et....
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