CHPs Contribute to Abdominal Aortic Anurrysm (AAA) Research)
Abdominal Aortic Aneurysm (AAA) is a life-threatening condition characterized by the extensive remodeling and breakdown of the extracellular matrix (ECM). Understanding the factors governing aortic instability - particularly the micro/nanoscale changes - is paramount for improving AAA management. A new publication, "Nano-mechanical Mapping of Human and Porcine Abdominal Aortic Aneurysm" uses advanced imaging techniques...
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Aging Unveiled: CHPs Reveal Widespread Tissue Damage and Reversible Collagen Breakdown in Aged Mice
Staining of collagen in multiple organs with Biotin-conjugated Collagen Hybridizing Peptides (B-CHPs). The black and white panels are an extraction of the fluorescent peptide signal, used for quantification of collagen damage. The universal process of aging involves the dysregulation of a wide spectrum of biological mechanisms. Using mouse models, DeLano et....
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