Damaged collagen detected by collagen hybridizing peptide as efficient diagnosis marker for early hepatic fibrosis
Liver fibrosis, a significant pathological consequence of chronic liver disease and damage, is characterized by the excessive accumulation of extracellular matrix (ECM) proteins. This build up of non-functional scar tissue progressively replaces healthy tissue in the liver, leading to conditions such as cirrhosis, liver failure, and heightened risk of liver cancer. With a high...
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Collagen Hybridizing Peptides (CHPs): Unraveling the role of Denatured Collagen in Neuroblastoma.
The complex interplay between the tumor microenvironment (TME) and cancer progression is a critical area of research, particularly in aggressive childhood cancers like neuroblastoma (NB). A recent study, “Unraveling the Role of Denatured Collagen in Neuroblastoma via Collagen Hybridizing Peptides,” published in July 2023, has shed light on the impact of thermal ablation on...
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Beyond Fibroblasts: CHPs provide Key Evidence for Keratinocyte-Driven Skin Development
Collagen is skin's foundation, but how it's truly built has been hidden – until now. Discover how see-through axolotls are providing an unprecedented window into this process, revealing secrets that could reshape skin science.
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