First Empirical Evidence of Collagen Damage during Bone Fracture
Bone is a remarkable material, strong enough to withstand impressive forces without fracturing. Despite decades of research, however, our understanding of the molecular mechanisms underlying bone’s fracture resistance has remained incomplete. It has long been hypothesized that collagen degradation occurs following bone fracture. Until recently, this hypothesis lacked empirical evidence due to a...
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Collagen denaturation is initiated upon tissue yield in both positional and energy-storing tendons
A great new article from a collaboration between Dr. Jeff Weiss's lab and our founder, Dr. Michael Yu's lab at the University of Utah. The new Acta Biomaterialia paper explores at what point collagen denaturation occurs in tendons under mechanical strain and how tendon type influences the mechanism of failure. Researchers evaluated functionally distinct...
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