We are excited to announce a research collaboration with Henkel Beauty Care Technologies (Germany), experts in skin physiology, and the developer of advanced human 3D reconstructed skin models. This interesting collaboration is investigating skin damage using their proprietary Phenion® Full-Thickness Skin Models and our CHPs. We hope to develop a useful skin testing kit together that can provide a standardized way to evaluate skin damage in vitro. Check...
Another great paper using CHPs! A recent article published in Wound Repair and Regeneration evaluated how the level of collagen denaturation within burned tissues influences the effectiveness of enzymatic debridement (removal of damaged tissue). They showed that low-temperature burns (<65 °C) had inadequate debridement, while high-temperature burns (>65 °C) had very effective debridement. By using CHPs, Sirius red (PSR), and second harmonic gener...
Another exciting article that was published by the Watt Lab (King's College) in PLoS One utilized CHP technology to examine differences in dermal development in mice caused by lysyl oxidase-like 2 (LOXL2) which contributes to the remodelling of the ECM. They used the new CHP to assess and quantify the difference in collagen fiber structure between a LOXL2 knock-out, knock-in and control mice from postnatal day 2 up to day 120.
Abstract: Lysyl oxidase-l...
