The Impact of Skeletal Muscle Contraction on CD146+Lin- Pericytes

The Impact of Skeletal Muscle Contraction on CD146+Lin- Pericytes
Interesting new work published in The American Journal of Physiology- Cell Physiology evaluated the ability of muscle-derived pericyte to contribute to skeletal muscle remodeling in response to training. The researchers used electric stimulation to contract muscles and monitor the response of pericyte cells. They found that the CD146+ Lin- pericyte cells were the most sensitive to contraction and they contribute to upregulating ECM remodeling and angio...

Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides

Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides
A great review article was recently published in the International Journal of Molecular Sciences that discusses how currently available collagen targeting methods are used for regenerative therapeutics. This article also compares the benefits and drawbacks of several collagen targeting strategies. (Spoiler: They highlight several key advantages CHPs have over other collagen-binding peptides). Very informative article and useful to those who are looking...
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