Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2

Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2
HOT OFF THE PRESS!!! A new article published in Frontiers in Immunology (impact factor: 4.72) utilized B-CHP to evaluate how the Zika virus influences renal function. The authors monitored fibrosis changes and collagen deposition in healthy and Zika infected mouse kidneys. The authors clearly link the Zika virus infection to kidney injury and elucidated the underlying molecular mechanisms for the first time. B-CHP enabled them to image the amount of da...

Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease

Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease
A newly published article in the American Journal of Physiology- Renal Physiology showed there was increased collagen remodeling in pateints with chronic kidney disease which is due to skeletal muscle fibrosis. This increase in collagen degradation was specifically visualized using F-CHP. This image shows damaged collagen (green), collagen IV (red), and cell nuclei (blue). This interesting work was performed by the Fry Lab (UTMB). Abstract: Muscle dysf...
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