New work from Dr. Karl Kadler's lab utilized CHPs to see how BiP influences the circadian rhythm of cells. They saw that BiP overexpression resulted in a more robust circadian rhythm but that it led to retention of procollagen in the ER as non-helical collagen and reduced the assembly of collagen fibers. They were able to visualize this by using F-CHPs. Great work and interesting findings! Abstract: ER stress and dysregulation of collagen synthesis are...