Direct Detection of Collagenous Proteins by Fluorescently Labeled Collagen Mimetic Peptides
For those of you interested in how CHP technology works, take a look at this schematic showing how single-stranded CHPs (formerly known as CMPs) are generated either from thermally dissociating the triple helix or by utilizing a photo-sensitive cage group that prevents self-trimerization completely. Once in a single-stranded conformation, CHPs can be used to bind to denatured collagen. This paper goes into detail on how CHPs binding mechanism works and...