An Anterior Cruciate Ligament Failure Mechanism

An Anterior Cruciate Ligament Failure Mechanism
A new publication in The American Journal of Sports Medicine used CHPs to evaluate the structural integrity leading to noncontact ACL failure as a result of strenuous repetitive impulsive athletic maneuvers. CHPs were used to visualize the molecular level damage to the collagen triple helix and show that repeated mechanical loading weakens the ACL. The figure shows the untested contralateral, unloaded knee (control knee) (A) and the mechanically tested...

Anterior Cruciate Ligament Tear Promotes Skeletal Muscle Myostatin Expression, Fibrogenic Cell Expansion, and a Decline in Muscle Quality

Anterior Cruciate Ligament Tear Promotes Skeletal Muscle Myostatin Expression, Fibrogenic Cell Expansion, and a Decline in Muscle Quality
Extra! Extra! Read all about it! In a newly published paper in the American Journal of Sports Medicine, a group of PhDs and Surgeons used our F-CHPs to evaluate the collagen turnover after a complete ACL tear. They visualized the collagen turnover using CHPs (Panel D) and quantified the signal. They found that there was a statistically significant increase in dynamic collagen remodeling in the injured vastus lateralis muscle (outer quad muscle) vs the ...
Please wait...

Subscribe to our newsletter

Want to be notified when our article is published? Enter your email address and name below to be the first to know!