Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease
A newly published article in the American Journal of Physiology- Renal Physiology showed there was increased collagen remodeling in pateints with chronic kidney disease which is due to skeletal muscle fibrosis. This increase in collagen degradation was specifically visualized using F-CHP. This image shows damaged collagen (green), collagen IV (red), and cell nuclei (blue). This interesting work was performed by the Fry Lab (UTMB).
Abstract: Muscle dysf...