Collagen denaturation is initiated upon tissue yield in both positional and energy-storing tendons

Collagen denaturation is initiated upon tissue yield in both positional and energy-storing tendons
A great new article from a collaboration between Dr. Jeff Weiss's lab and our founder, Dr. Michael Yu's lab at the University of Utah. The new Acta Biomaterialia paper explores at what point collagen denaturation occurs in tendons under mechanical strain and how tendon type influences the mechanism of failure. Researchers evaluated functionally distinct tendons using positional tendons (rat tail tendons) and energy-storing tendons (rat flexor digitorum ...

Our Founder Speaks at Seoul Forum 2020!!

Our Founder Speaks at Seoul Forum 2020!!
Check out this great video of our Founder, Dr. Michael (Seungju) Yu giving a presentation about the story of 3Helix and our technology at the Seoul Forum 2020 organized by Seoul Economic Daily. This is a great honor as previous speakers include Nobel Laureates. Dr. Yu does a great job at explaining our technology in an easy to understand manner that is targeted to an audience without a scientific background. If you have ever wondered what CHPs are and h...

Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues

Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues
Fig. 1. Study overview. (A) Rat tail tendon fascicles were loaded in creep-fatigue to 40% of the ultimate tensile strength (UTS) until tissue failure. Incremental levels of fatigue were defined as the peak cyclic (creep) strain at 20, 50, and 80% of cycles to failure. (B) To label and quantify denatured collagen, we stained mechanically loaded fascicles with fluorescent CHP, which hybridizes to unfolded collagen ? chains. The amount of denatured collag...

New Distibutor in Japan!!

New Distibutor in Japan!!
As 3Helix continues to grow and expand, we are excited to announce that we have added a new distributor in Japan! Now researchers can have access to our CHP products through the very popular and well-known, Iwai Chemicals Company! We look forward to a long and fruitful partnership with this great company and we hope this makes it even easier for researchers to try our products. Check out their WEBSITE HERE ...

New partnership in the field of collagen research in the skin!

New partnership in the field of collagen research in the skin!
We are excited to announce a research collaboration with Henkel Beauty Care Technologies (Germany), experts in skin physiology, and the developer of advanced human 3D reconstructed skin models. This interesting collaboration is investigating skin damage using their proprietary Phenion® Full-Thickness Skin Models and our CHPs. We hope to develop a useful skin testing kit together that can provide a standardized way to evaluate skin damage in vitro. Check...

We will be moving to our new home at Altitude Labs!

We will be moving to our new home at Altitude Labs!
We are excited to announce that we will be joining a brand new biotech incubator, Altitude Lab in January 2021! This is a great opportunity for small start-up companies looking to learn and grow while remaining in the SLC valley. This will help cultivate a culture and community of scientists in the biotech industry right in the foothills of the Wasatch. Very thankful to Chris Gibson from Recursion and Center for Technology & Venture Commercializatio...

Exciting New Partnership With Dr. Alastair Burt and Newcastle Molecular Pathology Node!

Exciting New Partnership With Dr. Alastair Burt and Newcastle Molecular Pathology Node!
We are excited to announce a new partnership with Newcastle MRC Molecular Pathology Node and Dr. Alastair Burt who is a leading expert in liver fibrosis. This partnership will combine the histopathology expertise from Dr. Burt and the Newcastle node along with the novel CHPs developed by 3Helix to investigate liver fibrosis. The goal of this collaboration will be to first establish CHPs as a reliable stain for evaluating fibrotic progression in liver di...

Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine

Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine
An interesting article evaluating the scar formation and cardiac function in pig heart after ischemia/reperfusion (IR) injury. Researchers used CHPs in this study to evaluate the damage immediately following IR and even compared this with Masson's Trichrome staining. They found that immediately after IR, the heart does see a decrease in cardiac function in terms of ejection fraction and fractional shortening but that these conditions did not worsen afte...

New Distributors Added!

New Distributors Added!
We are excited to announce our new distributors! Now our users can order CHPs from Neobioscience Technology (China) and ONS Bio (USA). We look forward to a long and fruitful relationship with both of these great companies and hope that this will make it even easier for our customers to get the products they need for their research! ...
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