A great new paper from Dr. Yang Li's group published in ACS NAno utilized in vivo CHPs with a Cy5 fluorescent tag to evaluate collagen destruction in the spine. This in-depth work identified collagen damage in three different animal models, compared the in vivo CHP imaging to micro-CT, histopathology, and performed tissue clearing methods to image using light-sheet fluorescence microscopy to truly identify the anatomic localization of CHP binding in the ...
During this holiday season, 3Helix is thankful for our amazing distributors and are excited to announce that we have added another one! We are happy to have Vector Biomed as our newest distributor, they can now help customers order CHPs in Singapore!! We look forward to a long and fruitful relationship with Vector Biomed! Check out their website HERE
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A great new article from a collaboration between Dr. Jeff Weiss's lab and our founder, Dr. Michael Yu's lab at the University of Utah. The new Acta Biomaterialia paper explores at what point collagen denaturation occurs in tendons under mechanical strain and how tendon type influences the mechanism of failure. Researchers evaluated functionally distinct tendons using positional tendons (rat tail tendons) and energy-storing tendons (rat flexor digitorum ...
Check out this brief article published by The National Institutes of Health about our work in the collagen field that has been supported by small business innovation research grants. Our CTO, Dr. Lucas Bennink, explains how instrumental the NIH SBIR grant has been for the progression and growth of 3Helix.
Check out the FULL ARTICLE HERE
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Check out this great video of our Founder, Dr. Michael (Seungju) Yu giving a presentation about the story of 3Helix and our technology at the Seoul Forum 2020 organized by Seoul Economic Daily. This is a great honor as previous speakers include Nobel Laureates. Dr. Yu does a great job at explaining our technology in an easy to understand manner that is targeted to an audience without a scientific background. If you have ever wondered what CHPs are and h...
Fig. 1. Study overview. (A) Rat tail tendon fascicles were loaded in creep-fatigue to 40% of the ultimate tensile strength (UTS) until tissue failure. Incremental levels of fatigue were defined as the peak cyclic (creep) strain at 20, 50, and 80% of cycles to failure. (B) To label and quantify denatured collagen, we stained mechanically loaded fascicles with fluorescent CHP, which hybridizes to unfolded collagen ? chains. The amount of denatured collag...
As 3Helix continues to grow and expand, we are excited to announce that we have added a new distributor in Japan! Now researchers can have access to our CHP products through the very popular and well-known, Iwai Chemicals Company! We look forward to a long and fruitful partnership with this great company and we hope this makes it even easier for researchers to try our products.
Check out their WEBSITE HERE
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We are excited to announce a research collaboration with Henkel Beauty Care Technologies (Germany), experts in skin physiology, and the developer of advanced human 3D reconstructed skin models. This interesting collaboration is investigating skin damage using their proprietary Phenion® Full-Thickness Skin Models and our CHPs. We hope to develop a useful skin testing kit together that can provide a standardized way to evaluate skin damage in vitro. Check...
We are excited to announce that we will be joining a brand new biotech incubator, Altitude Lab in January 2021! This is a great opportunity for small start-up companies looking to learn and grow while remaining in the SLC valley. This will help cultivate a culture and community of scientists in the biotech industry right in the foothills of the Wasatch. Very thankful to Chris Gibson from Recursion and Center for Technology & Venture Commercializatio...
We are excited to announce a new partnership with Newcastle MRC Molecular Pathology Node and Dr. Alastair Burt who is a leading expert in liver fibrosis. This partnership will combine the histopathology expertise from Dr. Burt and the Newcastle node along with the novel CHPs developed by 3Helix to investigate liver fibrosis. The goal of this collaboration will be to first establish CHPs as a reliable stain for evaluating fibrotic progression in liver di...
