Extra! Extra! Read all about it! In a newly published paper in the American Journal of Sports Medicine, a group of PhDs and Surgeons used our F-CHPs to evaluate the collagen turnover after a complete ACL tear. They visualized the collagen turnover using CHPs (Panel D) and quantified the signal. They found that there was a statistically significant increase in dynamic collagen remodeling in the injured vastus lateralis muscle (outer quad muscle) vs the uninjured muscle in the opposite leg (Panel F). They compared these results with other upregulated cells and ECM biomarkers and concluded that there is an increase in collagen turnover after ACL tear leading to a decrease in muscle quality.


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